Fully Automatic Animal Blood Cell Analyzer DH-760LAB
Key words:
Classification:
- Product Description
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Dynamic Hematoanalysis | Physical Research Applications
·To detect the most fundamental physiological/pathological responses of the organism following an experimental intervention or product implantation.
·To provide objective and quantifiable evaluation criteria for efficacy, toxicity, and biocompatibility.
·To link fundamental cell biological phenomena with overall animal physiological and pathological manifestations, and to promote the translation of scientific discoveries into practical applications.
Application in Scientific Research
Disease Model Research and Evaluation
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· Mechanism Investigation : Regular monitoring of changes in the quantity and quality of blood cells in spontaneous or induced disease models.
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· Model Validation : Confirming the successful establishment of a disease model by analyzing routine blood parameters in model animals.
Pharmacology and Toxicology Research
Efficacy Evaluation
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· Chemotherapeutic Agents : While evaluating the anti-tumor efficacy of chemotherapeutic drugs in tumor models, it is essential to concurrently monitor their myelosuppressive toxicity.
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· Leukocyte-/Platelet-Boosting Drugs : Directly assess whether such new drugs can effectively increase the counts of the corresponding blood cells.
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· Anti-inflammatory/Immunomodulatory Agents : Evaluate drug efficacy by observing changes in the differential count of white blood cells.
· Safety Evaluation (Toxicology) ：This is a mandatory step in the research and development of new pharmaceuticals.
Immunology and Vaccine Development
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· Immune Response Monitoring : Assess the level of the body's immune response following vaccination or administration of an immunostimulant.
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· Vaccine Adjuvant Evaluation : Evaluate whether a novel adjuvant can elicit an effective immune response without inducing excessive or harmful inflammatory reactions.
Genetics and Genetic Engineering
· In genetically modified animal models, such as gene knockout and gene overexpression, blood cell analyzers can be used to identify gene function.
Nutrition and Comparative Medicine
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· Nutritional Research : To investigate the effects of specific nutrient deficiencies or excesses on animal hematopoiesis (blood cell formation).
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· Comparative Medicine : By analyzing basic blood cell parameters across different species and animal strains, this research aims to identify more suitable animal models for human disease studies and to enhance our understanding of physiological differences between species.
Applications in Biomedical Device Development
Biocompatibility Evaluation of Medical Devices
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· Implantable Devices : For long-term implants such as cardiovascular stents, artificial joints, and bone plates, it is necessary to monitor inflammatory responses and potential infections in animals.
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· Blood-Contacting Devices : Confirm the success of the disease model establishment by analyzing routine blood parameters in the model animals.
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· Hemolysis : Monitor changes in red blood cell count, hemoglobin, and hematocrit to calculate the hemolysis rate.
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· Thrombogenicity : Monitor the dynamic changes in platelet count to determine if the device activates the coagulation system.
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· Inflammatory Response : Observe the increase in white blood cells, particularly neutrophils.
Surgical Techniques and Device Validation
When developing new surgical techniques or devices (e.g., novel electrocautery units, laser surgery systems), postoperative routine blood tests in animals can be used to indirectly assess the extent of tissue trauma and systemic inflammatory response caused by the procedure.
Evaluation of Novel Drug Delivery Systems
For systems such as nanomedicines and oncolytic viruses, the analyzer can be used to evaluate whether the delivery system affects hematopoietic function and the immune system, as well as to determine its circulation time in the blood.
Development of Blood Products & Consumables
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· Artificial Blood Substitutes : Evaluation of oxygen transport capability and in vivo duration via RBC parameter monitoring.
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· Blood Preservation Solutions : Assessment of protective efficacy for RBC and platelet viability in stored blood.
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· Blood Purification Consumables : Determination of treatment-induced blood cell damage from devices like dialyzers/plasmapheresis systems.
Authoritative Certification | Reliable Results
• CNAS-accredited national blood measurement laboratory with traceable results.
• Globally recognized for achieving eight world-first innovations in routine blood testing.
• Holds over 1,600 global patents, ranking 15th among all global IVD companies.
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