NVision POLARIS Hyperpolarized MRI System Ushers in a New Era of In Vivo Metabolic Visualization!
Release time:
2025-12-12
Beyond Anatomy: Visualizing Cellular Metabolism in Real Time!
NVision POLARIS HP-MRI System
In the field of life sciences, real-time and precise observation of live metabolic processes has long been a goal pursued by scientists. While traditional MRI technology can provide structural information at the tissue level, it struggles to capture the dynamic changes in cellular metabolism. Now, the NVision POLARIS hyperpolarized MRI system, with its revolutionary technological advantages, is bringing unprecedented breakthroughs to metabolic imaging research.
What is hyperpolarized MRI? Why is it so important?
Hyperpolarized MRI enables real-time, non-invasive visualization of metabolic processes within living organisms. In contrast to traditional MRI, which can only observe slow structural changes in tissues, hyperpolarized MRI captures dynamic metabolic changes at the cellular level, providing critical insights for studying disease mechanisms, evaluating drug responses, and monitoring treatments.
POLARIS: Revolutionizing Metabolic Imaging in Three Steps
The POLARIS hyperpolarized MRI system utilizes parahydrogen-induced polarization (PHIP) technology, enabling the hyperpolarization preparation of metabolic substrates at room temperature in just 2–3 minutes, with a signal enhancement exceeding 10,000-fold. The procedure is remarkably straightforward:
1. Preparation: Use natural metabolic precursors (such as ¹³C-pyruvate).
2. Polarization: Rapidly enhance the signal via the POLARIS device.
3. Scanning: Inject the hyperpolarized metabolite and perform imaging using a conventional MRI scanner.
PHIP vs. d-DNP
The POLARIS hyperpolarized MRI system is particularly suited for high-frequency, multi-sample metabolic imaging experiments in research settings, offering researchers a stable, efficient, and cost-effective hyperpolarization solution. The parahydrogen-induced polarization (PHIP) technology it employs demonstrates significant advantages over methods such as dynamic nuclear polarization (d-DNP) in several aspects:
| Comparison Dimension | PHP | d-DNP |
|---|---|---|
| ✔ Polarization Time | 2–3 minutes | 1 hour to several hours |
| ✔ Operating Temperature | Room temperature, no cryogenics required | Requires cryogenic environments (e.g., liquid nitrogen) |
| ✔ System Size | Compact, portable, mobile | Large, fixed installation |
| ✔ Installation Difficulty | Plug-and-play, no infrastructure modification needed | Requires specialized lab facilities |
| ✔ Operating Cost | Low consumables, low maintenance | High energy consumption, high maintenance costs |
| ✔ Applicable Scenarios | Labs/core facilities, high-frequency experiments | Mostly limited to large imaging centers |
POLARIS: The Plug-and-Play Revolution in Hyperpolarized MRI
1. Mobile and Flexible: Your "Mobile Hyperpolarization Lab"
• Compact and Portable: The POLARIS hyperpolarized MRI system features an integrated, compact design with a small footprint. Equipped with silent swivel casters, it can easily move through lab corridors, elevators, and be flexibly transferred between different floors or laboratories.
2. Easy Installation: 2-Step Setup, Ready on the Same Day
• Connect to Power: Plug into a standard 220V power outlet.
• Connect Gas Lines: Connect to regular nitrogen (N₂) and parahydrogen (p-H₂) supplies.
3. Simple Operation: One-Button Polarization, Samples Ready in 3 Minutes
• Standardized Workflow: Only three steps: mix, inject, and start.
• One-Button Start: Press the "Start" button, and the system automatically completes the entire polarization process, achieving signal enhancement within 90 seconds.
• Intuitive Interaction: The touchscreen interface provides clear guidance, real-time status updates, and self-diagnostic fault alerts, making the preparation process transparent, controllable, and worry-free.
The POLARIS hyperpolarized MRI system has already demonstrated great potential across multiple research fields
1. Cancer Metabolism Research: Real-time monitoring of tumor metabolic reprogramming, evaluating drug responses and resistance mechanisms.
2. Neuroscience: Observing neuronal glucose metabolism to study brain function and disease mechanisms.
3. Cardiovascular Diseases: Early detection of myocardial metabolic abnormalities and assessment of treatment responses in heart failure.
4. Metabolic Disorders: Studying metabolic functional changes in organs such as the liver and kidneys.
Beijing Yiren Hengye: Providing You with Complete Scientific Research Solutions
As NVision's partner in China, Beijing Yiren Hengye Technology Co., Ltd. offers comprehensive end-to-end services—from equipment supply and consumables provision to technical support and research collaboration—delivering stable, reliable, and efficient hyperpolarization support for your work.
Feel free to reach out via private message for more technical materials, demonstration arrangements, or partnership inquiries.
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