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Intermittent Fasting Improves High-Fat Diet-Induced Obesity Cardiomyopathy via Alleviating Lipid Deposition and Apoptosis and Decreasing m6A Methylation in the Heart

Xu Z, Qin Y, Lv B, Tian Z, Zhang B. Intermittent Fasting Improves High-Fat Diet-Induced Obesity Cardiomyopathy via Alleviating Lipid Deposition and Apoptosis and Decreasing m6A Methylation in the Heart. Nutrients. 2022 Jan 7;14(2):251.

Mouse

Cardiovascular Diseases

2022

Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress

Zhao J, Yu L, Xue X, Xu Y, Huang T, Xu D, Wang Z, Luo L, Wang H. Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress. Redox Biol. 2023 Feb;59:102594.

Mouse

Neurological Diseases

2023

MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway

Lei W, Li J, Li C, Chen L, Huang F, Xiao D, Zhang J, Zhao J, Li G, Qu T, Zhou H, Liao Y, Chen M. MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway. J Cell Mol Med. 2021 Apr;25(7):3182-3193.

Rat

Cardiovascular Diseases

2021

Betulinic Acid Improves Cardiac-Renal Dysfunction Caused by Hypertrophy through Calcineurin-NFATc3 Signaling

Hong MH, Na SW, Jang YJ, Yoon JJ, Lee YJ, Lee HS, Kim HY, Kang DG. Betulinic Acid Improves Cardiac-Renal Dysfunction Caused by Hypertrophy through Calcineurin-NFATc3 Signaling. Nutrients. 2021 Sep 30;13(10):3484. doi: 10.3390/nu13103484.

Rat

Cardiovascular Diseases

2021

Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction

Yang H, He Y, Zou P, Hu Y, Li X, Tang L, Zhu Z, Tai S, Tu T, Xiao Y, Chen M, Wu C, Zhou S. Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction. Cell Death Dis. 2020 Nov 26;11(11):1014.

Mouse

Cardiovascular Diseases

2020

Intermittent short-duration reoxygenation relieves high-altitude pulmonary hypertension via NOX4/H2O2/PPAR-γ axis

Li S, Lyu Q, Shi Q, Bai Y, Ren X, Ma J. Intermittent short-duration reoxygenation relieves high-altitude pulmonary hypertension via NOX4/H2O2/PPAR-γ axis. Clin Sci (Lond). 2024 Feb 7;138(3):103-115.

Mouse

Cardiovascular Diseases

2024

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