EMMS Forced Maneuvers (FM) System
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- Product Description
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The EMMS Forced Maneuvers (FM) system requires anesthesia and endotracheal intubation. It is equipped with convenient and easy-to-operate transpulmonary pressure detection. The main parameters are the same as those for human lung function testing: respiratory rate, tidal volume, airway resistance, dynamic lung compliance, FEV, FVC-forced vital capacity, FRC-functional residual capacity, TLC-total lung capacity, Cchrod-static lung compliance and other indicators. It can also be expanded to detect ECG, arterial classification blood pressure and other indicators. It can be applied to the study of chronic obstructive pulmonary disease, emphysema, pulmonary fibrosis, silicosis, acute lung injury, mechanical ventilation-induced lung injury, etc. The system can also detect all indicators of the R&C system, and because it comes standard with transpulmonary pressure detection, it can be tested when the animal is breathing naturally without the assistance of a ventilator, so the animal's natural and true tidal volume and Indicators such as respiratory rate. The disadvantage of the FM system is that it uses a large number of precision valves to control the animals to breathe hard, and the crystallization of atomized particles will block the valve channel, so the system does not have atomization drug delivery function, and has limitations on the use of acetylcholine attack required for asthma research. However, the system provides traditional intravenous drug delivery, so it can also be used in asthma research that requires drug attack.
Multiple test combinations of FRC, QV, and PV can be completed within five minutes and output rich indicator data;
Continuously output respiratory function data such as airway resistance Rl, dynamic lung compliance Cdyn, tidal volume, etc.
Detect transpulmonary pressure to obtain more accurate data results, eliminating the influence of external factors such as ventilators;
The test allows for both using a ventilator and not using a ventilator. The standard configuration is not using a ventilator to obtain more realistic data results such as tidal volume and respiratory rate.
The host has a built-in small computer to process the raw data, making the raw data sampling rate as high as 60kHz;
The USB data cable is used to transmit data between the external computer and the host, and the COM port connection is used to transmit the software's operating instructions to the host, avoiding the use of the USB data cable to transmit data and command signals in both directions.
It can detect direct physiological data such as FRC functional residual capacity, FEV, FVC forced vital capacity, quasi-static lung compliance, TLC total lung volume, IC inspiratory capacity, VC vital capacity, etc., and output various lung function indicators that are almost consistent with human medical lung function test methods. It is currently the animal lung function test system with the most complete test indicators;
Requires moderate anesthesia and endotracheal intubation (invasive testing);
Data is presented immediately without waiting; various graphics and statistical analysis data can be exported;
Optional external devices for cardiovascular research such as arterial blood pressure and ECG can be used;
It can be connected to oxygen, CO, CO2, nitrogen and other gases to meet various experimental schemes.
Product Application:
The FM system is an essential tool for the study of COPD, acute lung injury, interstitial lung disease, etc., and is widely used in preclinical studies of various lung disease models;
The standard configuration is suitable for mice, rats, and guinea pigs. Special Plethysmographs for various common experimental large animals such as rabbits, cats, dogs, pigs, monkeys, etc. can be customized;
Technical parameters:
Animal lung function testing system
The basic function is to detect all physiological data related to lung function. It can measure and analyze a series of experimental data on anesthetized mice, rats/guinea pigs, including the test of forced vital capacity and other related data;
The host pressure accumulator is made of metal, which can ensure that large animals from rodents to monkeys can be detected without replacing the host;
The data and commands are transmitted unidirectionally through different channels. The USB port transmits the original data, and the COM port transmits the computer's control commands to the instrument, avoiding the hidden danger of buffer overflow and interruption of data collection caused by bidirectional transmission of a single USB line;
Detection speed and accuracy: All forced lung function data including FEV(x), FEF(x), FVC, FRC, FEVpef, MMFF, Cchord, Resistance/Compliance, etc. can be measured within five minutes;
Sampling rate: 60kHz
Airflow sensor sensitivity: 0.035 mV/V/cmH2O
Differential pressure sensor sensitivity: 0.043 mV/V/cmH2O
Repeatability:>99.95%
Long term stability (1 year calibration drift): <0.05%
Plethysmograph signal-to-noise ratio in quiet environment: 60:1;
In noisy environments: 7.6:1
Circuit noise: <1 bit
Testing method: Use classic spirometry to test lung function;
Data Report: The software automatically generates data reports that can be printed directly;Statistical data and original data for academic reports can be directly obtained, avoiding the time-consuming and labor-intensive manual calculations with large errors.
Test parameters: basically the same as those of human lung function tests; mainly include the following test items
Client List:
Department of Respiratory Medicine, Shanghai First People's Hospital
Daping Hospital Affiliated to the Third Military Medical University (Field Trauma Research Institute)
The First Affiliated Hospital of Lanzhou University
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