Laser Speckle SIM BFI-WF
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- Product Description
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The laser speckle blood flow imager is designed with the emerging LSCI (laser speckle contrast imaging) technology. With its unique technical advantages of non-contact, high-resolution, and full-field rapid imaging, it provides a new and effective means of blood flow monitoring and blood flow imaging for clinical medicine and basic research in life sciences. The instrument does not require any contrast agent, and its time resolution can reach milliseconds and its spatial resolution can reach micrometers, which enables scientific researchers and medical personnel to observe the blood flow distribution state of microvessels and the relative changes of blood flow values in real time. The instrument can be used in the fields of basic research in life sciences, new drug development, and blood flow monitoring in multiple clinical departments.
1. Fast, full-field blood flow imaging with temporal resolution down to milliseconds and spatial resolution down to micrometers
2. No mechanical scanning, no contrast agent, non-contact imaging
3. Can conduct qualitative and quantitative analysis on changes in blood flow velocity
4. Using an algorithm that corrects static tissue structure interference and multiple scattering effects, the accuracy of quantitative analysis of blood flow velocity is significantly improved;
5. Highly coherent and stable laser light source and 12-bit low-noise fast camera ensure excellent long-term stability of flow velocity measurement;
6. Integrated color imaging illumination light source and blood flow imaging laser light source, automatic switching of dual filter channels can achieve zero interference between color imaging and blood flow imaging, greatly simplifying user operations;
7. Unique parallel image reconstruction algorithm realizes high-speed blood flow image reconstruction and flexible configuration of real-time data filtering;
8. It can conduct real-time online analysis and offline loading analysis of the average blood flow in the ROI, and supports the drawing, copying and deletion of any shape and number of ROIs. The position and size of the ROI can be adjusted freely by dragging and dropping;
9. It can perform real-time online analysis and offline loading analysis of blood vessel diameter values, and supports the drawing, copying and deletion of any number of blood vessel diameters.
10. It has the function of expanding the measurement of hemodynamic multi-parameters, realizing the simultaneous measurement of blood flow, blood oxygen and blood volume parameters;Changes of microcirculation in end-toe after sciatic nerve anesthesia block
Changes of microcirculation at the end of toes after sciatic nerve anesthesia block
Before acupuncture After acupuncture
During the PDT treatment of port-wine stains, the blood vessels at the lesion are gradually blocked.
References:
1. X. Wu, J. Li, K. Joypaul, WW Bao, D. Wang, YJ Huang, PC Li, and W. Mei, Blood flow index as an indicator of successful sciatic nerve block: A prospective observation study using laser speckle contrast imaging. British Journal of Anaesthesia, 1-8 (2018)
2. Jiang Meijun, Chu Zhigang, Xie Qionghui, Huang Wenwei, Ruan Jingjing, Xie Weiguo, Application of laser speckle blood flow imaging in predicting wound healing time in burn patients, Chinese Journal of Burns, 2016, 32(12): 721-724. (Wuhan Third Hospital)
3. Wu Xixi, Feng Aiping, Laser speckle imaging observation of common warts before and after pulse dye laser treatment, Chinese Journal of Dermatology, 2016, 49 (3): 183-185. (Huazhong University of Science and Technology Union Hospital)
4. Chen D, Ren J, Wang Y, Zhao H, Li B, Gu Y. Relationship between the blood perfusion values determined by laser speckle imaging and laser Doppler imaging in normal skin and port wine stains. Photodiagnosis PhotodynTher. 2016 Mar, 13: 1-9. (301 Hospital)
5. Ren J, Li P, Zhao H, Chen D, Zhen J, Wang Y, Wang Y, Gu Y. Assessment of tissue perfusion changes in port wine stains after vascular targeted photodynamic therapy: a short-term follow-upstudy. LasersMed Sci. 2014 Mar, 29(2): 781-788. (301 Hospital)
6. Ren Jie, Basic research on non-invasive detection of skin microvessels using laser speckle imaging and optical coherence tomography, Chinese Journal of Laser Medicine, 2012, 21(5): 309. (301 Hospital)User list:
Chinese People's Liberation Army General Hospital
Union Hospital Affiliated to Huazhong University of Science and Technology
Tongji Hospital Affiliated to Huazhong University of Science and Technology
Guangzhou Military Region Wuhan General Hospital
The First Affiliated Hospital of Jinan University
Chengdu Military Region General Hospital
Wuhan First Hospital
Wuhan Third Hospital
Guangzhou University of Chinese Medicine
Fujian Normal University
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