Isolated Heart Perfusion System AD Langendorff
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- Product Description
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The isolated heart perfusion method can directly study the cardiac function of animals without the influence of other physiological regulation of the body. The isolated heart-related research of small animals has become an indispensable part of cardiovascular research due to its advantages such as high reproducibility and low cost. This system can perform Langendorff perfusion experiments on small hearts of mice, rats and guinea pigs. You can easily switch between constant flow or constant pressure mode with the push of a button. The specially designed dual-chamber system allows two different perfusates to be quickly switched during the experiment.
• Lightweight system saves bench space
• Water jacket to maintain constant temperature
• Easily switch between constant current and constant voltage modes with the push of a button
• Monitor, record and display coronary artery function and perfusion pressureReal-time recording and analysis
• Medical device testing
• Artificial heart development
• Ischemia/reperfusion studies
• Pharmacology/toxicology studies
• Myocardial function
• Hypertrophy, infarction, cardiomyopathy and other disease models
• Systemic circulation or ventricular studiesCoronary artery function
Technical parameters:
1. The perfusion device is suitable for animals: rats and mice.
2. Perfusion speed control: The pump speed is controlled by the controller, which has an automatic feedback adjustment function and outputs the pump speed to the recorder.
3. Perfusion mode: one-button switch between constant pressure and constant current
4. Number of perfusion fluid storage tanks: 2. You can freely switch between two different perfusion fluids during the experiment.
5. Temperature control accuracy: +-0.1 degrees
6. Temperature control stability: +-0.1 degrees
7. Peristaltic pump and controller
8. Pressure-flow feedback design allows cross-flow or constant pressure perfusion
9. Coronary flow: can be accurately measured
10. Control voltage: 0 - +5 V
11. Filter setting: 0.5 Hz or 1 HzReferences:
Targeted deletion of Puma attenuates cardiomyocyte death and improves cardiac function during ischemia-reperfusion
Lipid Emulsion Reverses Bupivacaine-induced Asystole in Isolated Rat Hearts
Assessment of Cardiac Function and Energetics in Isolated Mouse Hearts Using 31P NMR SpectroscopyUser Unit:
Beijing University
Capital Medical University
China Academy of Chinese Medical Sciences
Academy of Military Medical Sciences
Fudan University
Shanghai Jiao Tong University
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