Cardiac Electrophysiology Fluorescence Mapping System Mappinglab OM-Systems
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MappingLab provides users of cardiac electrophysiology research with a fluorescence mapping system that is simple to operate and has powerful analysis capabilities. It can simultaneously record multi-point action potential signals and calcium signals, and is a powerful tool for cardiac electrophysiology research.
Application of fluorescence mapping in cardiac electrophysiological researchFluorescence mapping technology is to load fluorescent dyes on myocardial tissue and record fluorescence changes with high-speed cameras to reflect changes in voltage or various ion concentrations in cardiac tissue. With the continuous improvement of high-speed cameras and the emergence of a variety of voltage-sensitive fluorescent dyes and ion-indicating fluorescent dyes, fluorescence mapping technology has gradually become a common tool for cardiac electrophysiology research, improving people's ability to observe myocardial electrical activity, calcium or other ion activity, and providing a powerful tool for explaining the cardiac electrophysiological mechanism and the mechanism of arrhythmia formation.
Fluorescence mapping system synchronously records 4096 channels of rabbit ventricular action potential and calcium activity (Langendorff perfusion)
Based on the recorded signals, more than ten types of information can be analyzed, including action potential conduction pattern, calcium activity time course, electrical alternation amplitude difference Map, APD, action potential conduction dispersion, conduction velocity, action potential depolarization time course, etc.Hardware System
MappingLab provides a variety of hardware systems, including OMS-PCIE-1001, OMS-PCIE-2001, and OMS-PCIE-2002. The system can be used to synchronously collect action potentials and calcium signals. The hardware system is capable of high-speed imaging of changes in weak fluorescence intensity between 425-900nm. The pixel size can be as small as 6.5 µm. By adjusting the object distance and the focal length of the lens group, the imaging can be changed in the range of 32 × 32 to 2048 × 2048 continuous pixels. The maximum quantum efficiency of the camera can reach more than 95%, ensuring high-speed acquisition with high signal-to-noise ratio.Recording software OMapRecord 3.0
•Programmable experiments, automatic recording, easy operation
• Various capture areas available from 32×32 to 2048×2048
• Easy-to-use acquisition configuration editing, which can easily configure various cardiac electrophysiology research experimental settings such as S1S1, S1S2, Alternans, etc.
• Multiple experimental configurations can be stored without repeated configuration
•Precise synchronization control including light source, stimulator, camera system and other peripherals, with synchronization rate accurate to 1µsAnalysis software OMapScope 3.2
• User-friendly interface and powerful functions
• One-click analysis of dozens of types, including activation sequence, APD, conduction dispersion, etc.
• Conveniently export data to readable file formats such as Matlab and Excel
• Multiple data visualization methods, intuitive and convenient analysis, analysis results can be exported in various forms such as video, color map, excel, etc.
• For ECG fluorescence signals, the software has set up a powerful filtering function, which can combine multiple filters to help users filter effectively
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