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Small Animal CT Hiscan VM Pro

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  • Product Description
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    Hiscan VM Pro is a fast and flexible in vivo micro-CT, mainly used for animal experiments. The cone beam X-rays used can see the internal structure of the sample, with a maximum resolution of 18μm. It can scan the whole body of small animals, such as mice and rats. At the same time, it can scan the selected area of interest, such as the head, spine, forelimbs, hind limbs, etc. of mice and rats. Different sizes of scanning beds are used according to the size of the sample. The unique design of the scanning bed can prevent small animals from escaping and falling into the machine.

    Hiscan VM Pro is equipped with high-precision adaptive respiratory gating, which can dynamically adjust the image acquisition speed according to the changes in the respiratory cycle, effectively reducing the chest movement artifacts caused by breathing. The protective housing is equipped with an anesthetic gas transmission interface and a variety of physiological monitoring equipment interfaces. The X-ray housing protection is safe and reliable, and the operator does not need additional protection. It is also equipped with a safety interlock device, which automatically turns off the X-ray when the door is opened to avoid misoperation and ensure the safety of the operator.

    It is widely used in preclinical research in subjects such as bone diseases, tumor diseases, cardiovascular diseases, inflammatory diseases, metabolic diseases, immunology, drug efficacy evaluation, and biomaterials.

     

    ► High-precision respiratory gating
    The respiratory signal is collected through high-precision respiratory gating, and images are acquired according to the respiratory signal waveform to obtain images of the same respiratory phase, thereby eliminating artifacts caused by respiratory movement and obtaining clear reconstructed images. At the same time, it is adaptive and automatically adjusts the image acquisition speed according to the respiratory frequency of different mice, and performs intelligent scanning.
    ► Precision designed scanning bed
    The precisely designed scanning bed is easy to operate. The small animals are placed in the transparent scanning chamber in the front, which is equipped with a camera to monitor the breathing of the small animals. It is also equipped with an anesthetic gas interface to ensure the stable breathing of the mice. It is also equipped with a continuous contrast agent injection interface for continuous contrast imaging for perfusion imaging.
    ► Multimodal image fusion technology
    A unique registration device is designed for multimodal image fusion. There are specific marking sites on the scanning bed, which can be imaged on a variety of devices, and image registration and fusion are performed based on these specific marking sites.
    ► GPU accelerated fast layered reconstruction
    By adopting an optimized fast layered reconstruction algorithm and using GPU for hardware acceleration, the reconstruction speed is increased to the point where the reconstruction is completed simultaneously at the end of scanning.

     

     

     

     

     

     

     

     

     

     

     

     

    参考文献:

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    8、The Role of Metal Nanoparticles in Influencing Arbuscular Mycorrhizal Fungi Effectson Plant Growth. Youzhi Feng, Shiying He, Ge Dong, Xiangui Lin et al. State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences. Institute of Agricultural Resources and Environment, Jiangsu Academy of Agricultural Sciences. School of Biological Science and Medical Engineering, Southeast University. Environ. Sci. Technol. 2013, 47, 9496-9504

    9、Target therapy of multiple myeloma by PTX-NPs and ABCG2 antibody in a mouse xenograft model. Cuiping Yang, Jun Dou, Ning Gu, et al. Department of Pathogenic Biology and Immunology, School of Medicine & Collaborative Innovation Center of Suzhou NanoScience and Technology, Southeast University. School of Biological Science & Medical Engineering & Collaborative Innovation Center of Suzhou NanoScience and Technology, Southeast University. ONCOTARGET . 2015,6(29),27714-27724

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    17、A fast beam hardening correction method incorporated in a filtered back-projection based MAP algorithm. Shouhua Luo, Huazhen Wu, Guang Li, Ning Gu, et al. Southeast University. Phys. Med. Biol. 2017,62, 1810–1830

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    19、A method of extending the depth of focus of the high-resolution X-ray imaging system employing optical lens and scintillator: a phantom study. Guang Li, Shouhua Luo, Yulin Yan, Ning Gu. School of Biological Science and Medical Engineering, Southeast University. BioMedical Engineering OnLine, 2015,14(1)

    20、Light field rendering of scintillator for X-ray imaging. Xiaolong Wang, Shouhua Luo, Guang Li, Jing Yang. School of Biological Science and Medical Engineering, Southeast University Acta Photonica Sinica. 2013, 42(12),1528-1533

     

    User list:
    Department of Medical Imaging, Nanjing Drum Tower Hospital
    School of Life Sciences, East China Normal University
    Jiangsu Provincial Key Laboratory of Biomaterials and Devices
    College of Biological Sciences and Medical Engineering, Southeast University
    Imaging Laboratory, Jiangsu Institute of Atomic Medicine
    Hunan Kenji Instrument Co., Ltd.

     

     

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