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Precise electrophysiological fundus functional imaging machine Roland RETIscan21-RETImap

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  • Product Description
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    Roland RETImap-SLO is an experimental device capable of evaluating local objective visual function and image evaluation of the fundus of animals of different sizes.
    One set of machines can realize multifocal ERG for large and small animals, full-color full-field ERG with continuously adjustable stimulation intensity, infrared fundus IR\FFA\AF\OCT imaging for large and small animals, and OCT retinal layer thickness measurement for different animals, and is equipped with a special constant temperature animal experimental table.

     

     

      

     

     

     

     

    Mouse multifocal ERG                                    Mouse OCT                                   Mouse FFA                       

       
     

     

     

    Mouse GFP/AF                               Pig Multifocal ERG                                   Pig OCT   

      

     

     

     

    Different color series stimulation intensity ERG

     

     

     

    Animal experiments on fundus diseases are inseparable from the quantitative evaluation of fundus structure and objective visual function. Roland's precise electrophysiological fundus functional imaging all-in-one RETImap can fully meet the needs of fundus animal experiments, and different functional modules can be modularly selected according to your experimental needs.

     

     

     

    RETImap-SLO basic module: IR+mfERG+Focal ERG+PERG+PVEP

     

     

     

     

     

     

     

    RETImap-SLO fundus imaging module: FFA, AF/GFP, OCT

     

     

    References

    1.Dai X, Zhang H, He Y, Qi Y, Chang B, Pang JJ. The frequency-response electroretinogram distinguishes cone and abnormal rod function in rd12 mice. PLoS One. 2015 Feb 23;10(2):e0117570. doi: 10.1371/journal.pone.0117570. PMID: 25706871; PMCID: PMC4338143.
    2.Harazny J, Scholz M, Buder T, Lausen B, Kremers J. Electrophysiological deficits in the retina of the DBA/2J mouse. Doc Ophthalmol. 2009 Dec;119(3):181-97. doi: 10.1007/s10633-009-9194-5. Epub 2009 Sep 17. PMID: 19760280.
    3.Gao G, He L, Liu S, Zheng D, Song X, Zhang W, Yu M, Luo G, Zhong X. Establishment of a Rapid Lesion-Controllable Retinal Degeneration Monkey Model for Preclinical Stem Cell Therapy. Cells. 2020 Nov 13;9(11):2468. doi: 10.3390/cells9112468. PMID: 33202702; PMCID: PMC7696075.
    4.Sharma R, Khristov V, Rising A, Jha BS, Dejene R, Hotaling N, Li Y, Stoddard J, Stankewicz C, Wan Q, Zhang C, Campos MM, Miyagishima KJ, McGaughey D, Villasmil R, Mattapallil M, Stanzel B, Qian H, Wong W, Chase L, Charles S, McGill T, Miller S, Maminishkis A, Amaral J, Bharti K. Clinical-grade stem cell-derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs. Sci Transl Med. 2019 Jan 16;11(475):eaat5580. doi: 10.1126/scitranslmed.aat5580. Erratum in: Sci Transl Med. 2019 Feb 6;11(478): PMID: 30651323; PMCID: PMC8784963.

     

     

    User list

    2 units in the laboratory of Sun Yat-sen University Zhongshan Ophthalmology Center
    Clinical Department of Sun Yat-sen University Zhongshan Eye Center
    Beijing Tongren Hospital
    Beijing Tongren Hospital Laboratory
    Peking Union Medical College Hospital
    Peking University Eye Center
    Peking University International Hospital
    Ophthalmology Hospital of China Academy of Chinese Medical Sciences
    Shanghai Fudan University Eye, Ear, Nose and Throat Hospital
    Shanghai Sixth People's Hospital
    Xiamen University Xiang'an Hospital
    Hebei Eye Hospital-Xingtai Laboratory
    Hebei Eye Hospital-Shijiazhuang
    Shanxi Eye Hospital
    Henan Provincial People's Hospital
    Lanzhou First People's Hospital

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